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Boster Bio
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Boster Bio
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Journal: BMC Ophthalmology
Article Title: Evaluation of serum YKL-40 and Galectin-3 as predictive biomarkers for proliferative vitreoretinopathy in rhegmatogenous retinal detachment: a prospective comparative study
doi: 10.1186/s12886-025-04553-3
Figure Lengend Snippet: Receiver operating characteristic (ROC) curves of serum YKL-40 and Galectin-3 for predicting proliferative vitreoretinopathy (PVR) development in rhegmatogenous retinal detachment (RRD) (a) ROC curve of serum YKL-40 demonstrating good discriminative performance for predicting PVR (AUC = 0.739, 95% CI = 0.621–0.856, p = 0.001; optimal cut-off = 26.9 ng/mL, sensitivity = 68.8%, specificity = 67.6%) (b) ROC curve of serum Galectin-3 showing moderate predictive accuracy (AUC = 0.643, 95% CI = 0.510–0.777, p = 0.045; optimal cut-off = 99.7 pg/mL, sensitivity = 62.5%, specificity = 58.8%) The diagonal line represents the reference line for random classification (AUC = 0.5)
Article Snippet: Each unit increase in
Techniques: